HeadMeds gives young people in the United Kingdom general information about medication. HeadMeds does not give you medical advice. Please talk to your Doctor or anyone else who is supporting you about your own situation because everyone is different. Please read more important details about our site.

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Mirtazapine

Return to Mirtazapine overview
  1. Use and Action
  2. Warnings and side effects
  3. Sex, drink, weight and everything else
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Mirtazapine can be used to treat the following conditions

Headmeds fills the medicines information gaps for young people - things you might want to know about meds like will it affect my sex life? Can I still study?  Can I drink?
Headmeds does not give medical advice so this is just general information.
Each medicine has a balance of good and bad effects, and each person gets their own individual effects.
You might want to know just one thing about your medicine, but on each page we have given you the ‘safety headlines’. Please read them as they are important.
We have included lots of information about each medicine - but if you want all the details, please look at the patient information leaflet - which is inside every pack. These leaflets are also at www.medicines.org.uk - where there will be the most up-to-date information.

Safety headlines

  • If you have taken more mirtazapine than it said on the label, you must see a doctor quickly – even if you do not feel any different.
  • Mirtazapine can make some people think about hurting themselves or committing suicide. You must go straight to hospital with your tablets if you have any of these thoughts.
  • Mirtazapine can also cause rare but serious side effects: allergic reactions (difficulty breathing, swelling of your face or throat, itching skin lumps), and bone marrow problems (symptoms could be high fever, sore throat or mouth ulcers). Go to a hospital if you get any of these symptoms with your medicine.
  • Do not take mirtazapine if you have taken a monoamine oxidase inhibitor antidepressant (MAOI) like moclobemide, phenelzine, isocarboxazid or tranylcypromine in the last 14 days.
  • Stopping mirtazapine suddenly can cause unpleasant withdrawal effects – go to your doctor if you want to stop, or if you are having these effects.
  • You might feel sleepy or dizzy, or less alert, in the first few days after taking mirtazapine – do not drive a car, ride a bike or operate machines until you see how this affects you.
  • If you are pregnant, or thinking of becoming pregnant, please read the pregnancy section (see Sex, drink and everything else) because mirtazapine may affect the developing baby.

Basic details

Mirtazapine is an antidepressant medicine

You can take mirtazapine as plain tablets, dissolving tablets or liquid

The plain tablets contain lactose and the melting tablets contain aspartame

The oral solution contains a small amount of alcohol and maltitol. Maltitol is related to fructose so if you have a problem with fructose this is best avoided.

  • The mirtazapine tablets that you swallow may not be suitable for you if you have problems eating some sugars or dairy (milk-based) foods, as they contain lactose.
  • The mirtazapine orodispersible (‘melt in your mouth’) tablets contain aspartame, which can be a problem for people who have a condition called phenylketonuria.
  • The oral solution contains a small amount of alcohol.
  • It also contains maltitol, which can be a problem for anyone who has an intolerance to a sugar called fructose.
  • Mirtazapine medicines do not contain any animal products.

Talk to your doctor or pharmacist before taking the medicine if any of these are a problem for you.

Reference Sources 

Search www.medicines.org.uk to find patient information leaflets and prescribing information on mirtazapine. Tablets, orodispersible tablets and liquid are listed separately. The SmPC lists all the inactive ingredients in the product so you can check against any allergies. If you are still unsure about this then speak to your pharmacist.

  • British National Formulary (BNF) and British National Formulary for children. Download the BNF/BNFC app (blue background) on to your mobile device. No longer available for public access via the web 
  • Taylor D, Barnes T, Young A. Maudsley Prescribing Guidelines in Psychiatry, 13th edition. Oxford: John Wiley & Sons, May 2018. ISBN: 978-1-119-44260-8
  • Royal Pharmaceutical Society. Medicines Ethics and Practice (42nd edition). London: RPS, 2018. Standards for pharmacists to work to. It is not a free publication
  • World Anti Doping Agency WADA Prohibited List https://www.wada-ama.org/en/resources/science-medicine/prohibited-list-documents 
  • Choiceandmedication; an independent source of information on many mental health conditions and their medicines with easy to read fact sheets www.choiceandmedication.org Personal subscriptions to download the app available for £1 per month (with proportionate discounts for longer periods) but your local mental health Trust may subscribe and provide information sheets for free.
  • Best Use of Medicines in Pregnancy (BUMPS). Information sheets on drugs in pregnancy http://www.medicinesinpregnancy.org/ 
  • Drugs and Lactation Database (LactMed). Information on drugs in breastfeeding https://toxnet.nlm.nih.gov/newtoxnet/lactmed.htm